To take part, you will need to register with IQVIA; this is the company collecting data on behalf of the ONS and the University of Oxford.
To register, call IQVIA on the number included in your letter. You will also need to provide your reference number; you will find this in the top right-hand corner of your letter. Your reference number starts with the letters “COV”. The telephone adviser will then be able to book you in for an appointment for a nurse or study health worker to visit your home to complete the study.Back to table of contents
The coronavirus (COVID-19) pandemic is having a major impact across the UK.
This study is trying work out how many people have already had COVID-19, even if they do not realise they have had it. We do this by asking questions, taking a swab from your nose and throat, and possibly taking a blood sample. One way the body fights infections like COVID-19 is by making small particles in the blood called “antibodies”. Scientists will measure levels of the COVID-19 virus in a nose and throat swab and levels of these antibodies in blood to work out who has COVID-19 now (with or without symptoms) and who has had it in the past. We will measure levels of the virus in a nose and throat swab once in everyone who joins the study. Only some of these people will be asked to give blood as well.
This study is running over the course of a year. There are three options open to you. You can just have one visit. You can have a visit every week for a month. Or, you can have a visit every week for a month and then continue to have visits every month for one year in total from when you joined the study. This is entirely voluntary. The nurse or study health worker can explain more about what this will involve.
The overall purpose of this study is to understand how many people of different ages across the UK have already had COVID-19. This will help the government work out how to manage the pandemic better moving forwards and protect the NHS from being overwhelmed.Back to table of contents
Antibodies are one way that your body fights an infection. It takes between two to three weeks for your body to make enough of them to fight the infection. When you get better, they still stay in your blood at low levels – this is what helps you not get the same infection again.Back to table of contents
The ONS is carrying out this study. The University of Oxford is sponsoring the study. We are working with other organisations to help collect and process the data for this study.
IQVIA will be responsible for arranging appointments, carrying out the nose and throat swabs, and taking the blood samples.
Scientists at the University of Oxford will be responsible for storing and processing the blood samples. They will create the antibody data for the ONS to analyse.
The National Biosample Centre are responsible for storing and processing the nose and throat swabs. They will create the virus data for the ONS to analyse.
The ONS and University of Oxford will analyse the data that have been processed by the University of Oxford and The National Biosample Centre.
This study will allow scientists to understand who has been infected with the coronavirus (COVID-19), even if they have not realised it at the time. This will help the government work out how to manage the pandemic better moving forwards and protect the NHS from being overwhelmed.Back to table of contents
You recently took part in a study run by the ONS and kindly agreed that the ONS could contact you again. You may have been contacted because you:
are currently taking part in the Labour Force Survey; it is also really important to us that you continue to take part in that study
have recently taken part in one of our online studies
The letter you have received will have been addressed to a household member who took part in a previous ONS study. However, in this study we are asking for all adults, teenagers and children aged two years or older in your household to take part.
In the first phase of this study, we are asking around 11,000 households from England to take part. Over the next year, we plan to ask around 132,000 households to take part from across the UK.Back to table of contents
Your participation is entirely voluntary, and you may withdraw at any time without providing a reason. Everyone in the household can make a different choice – it is not necessary for everyone to do the same. If you do take part, you may withdraw from the study at any time without giving a reason and without penalty. Parents or carers may also withdraw their child from the study at any time without giving a reason.
This is your chance to be involved in a unique study that will help scientists work out how many people have already been infected with the coronavirus (COVID-19). If you are still not convinced, you do not have to take part if you do not want to.Back to table of contents
Anyone in the household aged two years or older can take part in this study. The only exception is adults who are not able to consent for themselves.Back to table of contents
If you have a hearing impairment and are unable to use the telephone, you can contact IQVIA by email at email@example.com to make an appointment. You will need to provide your reference number in your email; you will find this in the top right-hand corner of your letter. Your reference number starts with the letters “COV”. An adviser will then contact you to book you in for an appointment for a nurse or study health worker to visit your home to complete the study.Back to table of contents
“If you or anyone currently resident in your household would like to take part in the study, then we will arrange for a study health worker to visit your home. By current resident, we mean a person who typically stays overnight in the household address at least four nights out of seven. A "household" is defined as either:
one person living alone; or
a group of people (not necessarily related) living at the same address who share cooking facilities and share a living room or sitting room or dining area”
Please call IQVIA, the company collecting the data, to book an appointment convenient for you. The reason for sending someone from the study to your home is so that you do not have to travel to a health centre. Everyone working for the study has received appropriate training.
Anyone in your home who wants to, can take part in the study. However, no one has to – we will include as many people as want to join.Back to table of contents
As a thank you for taking part, everyone, including children, who takes part in the study will receive a voucher.
You will be offered a voucher every time you participate in the study.
To find out more, see your invitation letter sent from the ONS.Back to table of contents
When the study health worker visits your home, they will first check that you still want to join the study and also ask if any other adults (aged 16 years or over) would like to join as well. We will ask anyone aged 16 years or over who wants to join to sign a consent form.
If an older child or teenager aged 10 to 15 years in your household wants to join the study, we will ask both them and their parent or carer to sign to say they are happy to be in the study. For younger children aged two to nine years, we will just ask their parent or carer to sign, but it is important that the child is also happy about this.Back to table of contents
A nurse or study health worker will visit your home. If you have been asked for a blood sample, it will be a nurse. The nurse and study health worker will use all the recommended precautions to protect you and other people in your home from getting the virus. The nurse or study health worker will then ask everyone who wants to join the study some questions about any symptoms they may have and about any contact with someone who had the coronavirus (COVID-19). They will also ask about gender, ethnicity, date of birth, occupation and who their GP is. We need to know who their GP is because the nose and throat swab results will be sent back to them.
The nurse or study health worker will show you how to take a swab from your nose and throat. This is straightforward and is being done in the drive-through testing centres. Anyone aged 12 years or over can take the swab themselves.
The reason for asking people to swab themselves is to protect nurses or study health workers in case people have COVID-19 and do not know it.
If a parent or carer and child aged 2 to 11 years have consented to take part in the study, a nurse or study health worker will ask the parent or carer to take their own swab before taking the nose and throat swab from the child. The swabs are the same size as used normally for children.
If you are aged 16 years or over, you may also be asked to take part in an optional part of the study. This will involve giving a five millilitre blood sample (about a teaspoonful), which will be taken by a nurse trained to take blood from your vein; this is no different to when you have a blood test at your local GP. When you book your appointment, someone from IQVIA will talk to you about this, but not all households will be invited to take part in this part of the study. You can always change your mind after booking the appointment, including on the day. Children and teenagers aged from 2 to 15 years will only have the nose and throat swabs.
This visit will take 15 to 30 minutes.Back to table of contents
You will also be asked whether you would be interested in repeating this visit. This is to see how exposure to the coronavirus (COVID-19) changes over time. You do not have to agree to continue to take part in study. You could agree to:
A: no further visits
B: further visits every week for one month (five visits in total)
C: further visits every week for one month, and then every month throughout the year after your first study visit (16 visits in total)
If you agreed to give blood the first time, we would like to take blood again every month, but not at weeks one, two or three.
Follow-up visits will take around 15 minutes.Back to table of contents
The first appointment will take around 15 to 30 minutes per person.
If you continue to take part in the study, the appointment will take around 15 minutes per person.Back to table of contents
Once you have made your appointment over the phone, there is nothing else for you to do. The nurse or study health worker will bring all necessary equipment with them to your home for the appointment. However, should anyone in your home develop coronavirus (COVID-19) symptoms before the nurse or study health worker visits, please contact IQVIA.Back to table of contents
We will link information from you in this study to data from the NHS and ONS about your health status, for example, whether you have visited hospital or a GP or had another test for the coronavirus (COVID-19). This is to try to work out what we need to do to keep the NHS going through this pandemic. We will do this for one year after your last visit.
We will only use names and date of birth where this is absolutely necessary to link to your NHS and ONS records. We will use your postcode to try to work out how COVID-19 is spreading around the country. At the point when they are collected in your home, all samples and study records will be identified only by a code for your household and each person in it joining the study, together with month and year of birth and not the actual date of birth.
Information that can identify you will only be held by the ONS and IQVIA for the purposes of the study.
Responsible members of the University of Oxford may be given access to data for monitoring and/or audit of the study, to ensure that the research is complying with applicable regulations.Back to table of contents
Your nose and throat swab will be tested at the National Biosample Centre using the standard test to find out if someone currently has the coronavirus (COVID-19), even if they do not have symptoms. We will send the result of this test back to your GP, who will be able to discuss it with you.
Your blood sample will be tested by scientists at the University of Oxford. They will look for the levels of antibodies against COVID-19 in your blood. You will not get the result from these antibody tests because they are currently only used in research and not yet approved by the Medicines and Healthcare products Research Agency.Back to table of contents
The nose and throat swab will be destroyed once the test is done.
We would like to keep any blood that is not used immediately for the antibody test for future research, including for better tests relating to the coronavirus (COVID-19). You do not have to agree to this. Your blood sample will either be used up or destroyed after five years.Back to table of contents
Your participation is entirely voluntary. You have the right to withdraw from the study at any time without explanation. This includes after you have arranged an appointment for a nurse or study health worker to visit your home and if you have already given a swab from your nose and throat and a blood sample.
If the tests have already been done when you change your mind, we will still use the data from them because they are very important for our study to get a good picture of who has had the coronavirus (COVID-19) across the UK. But if you no longer wish for any leftover blood to be stored, we will destroy it. You can also decide that you do not want us to get any more information about you from the NHS if you leave the study.Back to table of contents
The samples that you take from your nose and throat will be tested at a national testing centre for the coronavirus (COVID-19) virus. We will tell you the results of these tests through your GP, who will be able to discuss them with you. You would not usually get these tests done. However, it is very important that if you develop symptoms of COVID-19, you follow the usual NHS guidance on Coronavirus symptoms and what to do – do not wait for the results of the tests done in this study. Whatever the results, it is also essential to keep following government guidance.
You will not get the result from the antibody tests because they are currently only used in research and are not yet approved by the Medicines and Healthcare products Research Agency.Back to table of contents
Yes, we will tell your GP that you are in this study, and we will send all the results from tests on your nose and throat swabs to them.Back to table of contents
The ONS will use the data from your nose and throat swab and blood sample, together with other data sources available to the ONS. We will get data on how much you have used the NHS from NHS Digital. NHS Digital is the NHS body that looks after all NHS data. We particularly want to find out how having had the coronavirus (COVID-19) infection in the past affects how much you need to use the NHS in future. This is to try to work out what we need to do to keep the NHS going through this pandemic.Back to table of contents
Taking part will not affect the medical care you receive, and there is no effect on any regular medication or other prescribed or over-the-counter medicines you might be taking. It is also fine to take part if you are involved in other research studies.
When blood is taken, there is a possibility of bruising and/or fainting; the nurses or study healthcare workers who will do this are trained to take blood to reduce this risk.Back to table of contents
Yes, this project has been given approval by South Central – Berkshire B Research Ethics Committee (20/SC/0195).Back to table of contents
If you have a question about how the ONS processes your personal data or want to find out more about your rights under data protection legislation, please see the ONS’ data protection page.
All personal data collected as part of this study will be processed in accordance with the Data Protection Act 2018.
We take our responsibilities to keep your personal information secure very seriously. As such, we take every reasonable precaution to ensure your information is protected from loss, theft or misuse. These precautions include appropriate physical security of our offices, controlled access to computer systems and use of secure, encrypted internet connections when collecting personal information.
The University of Oxford and ONS are the joint Data Controllers and are responsible for looking after your information and using it properly.
Data protection regulation requires that we state the legal basis for processing information about you.
In the case of the research, the University of Oxford is carrying out this research as “a task in the public interest”. More information is available in their privacy notice.
In the case of the research, the ONS is processing this information as it is necessary for us to perform our official function, which is to produce statistics for the public good. Your information will be treated as confidential as directed by the Code of Practice for Statistics. It will only be held for as long as it is being used for producing statistics. Study information may be provided to other approved organisations or researchers for statistical purposes only.
We will be using information from you and NHS Digital. NHS Digital is the NHS body that looks after all NHS data. To do this study, we will use the minimum personally identifiable information possible.
IQVIA and the ONS will keep identifiable information about you from this study for five years after the study has finished.Back to table of contents
To book an appointment to take part, call IQVIA on the number in the letter that was sent to you.
IQVIA opening times are:
Monday to Thursday – 9:00am to 9:00pm
Friday – 9:00am to 8:00pm
Saturday – 9:00am to 5:00pm
Sunday – 9:00am to 5:00pm
If you have any further questions on the COVID-19 Infection Survey (CIS), you can send an email to COVIDfirstname.lastname@example.org.Back to table of contents