Among the 24 cancers examined here, 1- and 5-year survival was highest for testicular cancer in men and melanoma of the skin in women. Survival for pancreatic cancer was the lowest at 1 and 5 years for men and women.
10-year survival predicted for patients who would be diagnosed in 2015 was highest for melanoma of the skin and lowest for leukaemia in both sexes.
The largest difference in 1-year survival between men and women was for bladder cancer, where 78.0% of men were expected to survive at least 1 year, compared with 66.9% of women.
5-year survival remains below 25% for cancers of the brain, liver, lung, mesothelioma, oesophagus, pancreas and stomach.
5-year survival is above 80% for breast cancer (women), testis and prostate cancer, and for thyroid cancer, Hodgkin lymphoma and melanoma of the skin in both sexes.
For 16 of the 24 cancers, 1-year survival for patients diagnosed between 2010 and 2014 was slightly higher than for the overlapping period 2009 to 2013 in at least 1 of the sexes. Differences in survival are mostly small, because many patients are included in both analyses.
Cancer survival is usually higher for younger patients. Two well-known exceptions are breast cancer in women, and prostate cancer, for which 1-year and 5-year survival are higher among some of the older age groups than the youngest age groups. This pattern was consistent for predicted 10-year survival.Back to table of contents
This bulletin presents estimates of 1-year and 5-year net survival (%) for all adults (aged 15 to 99 years) diagnosed between 2010 and 2014 and followed up to 31 December 2015. Predicted estimates of 10-year net survival are also presented for patients who would be diagnosed in 2015. The estimates of 1-, 5- and 10-year survival are based on patients diagnosed with 1 of 24 common cancers in England. Taken together, these cancers comprise 91.1% of all newly diagnosed cancers (based on the number of cancer diagnoses in England ).
Data are presented for men, women and both sexes combined. Five of the cancers only occur in 1 sex (cervix, ovary, uterus, testis and prostate). We present survival for cancer of the larynx only in men, and for breast cancer only in women, because those 2 cancers are rare in the opposite sex. We report survival by age group and for all ages combined. To allow the comparison of survival between cancers with a different age profile, all-ages survival estimates are age-standardised. Confidence intervals are provided, to indicate the precision of the survival estimates.
We have published 1-year and 5-year survival in this bulletin for many years, but this is the first time that 10-year survival estimates have been presented, using the hybrid approach . Results are only presented if sufficient data were available to make robust estimates of survival. Further information on the methods can be found in the Background notes .Back to table of contents
This publication is produced in partnership with the Cancer Research UK Cancer Survival Group at the London School of Hygiene & Tropical Medicine.
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Age-standardised estimates of 1-year net survival are presented below for men (Figure 1) and women (Figure 2). 1-year survival was lowest for pancreatic cancer in both sexes, at 21.1% for men and 22.9% for women. The highest 1-year survival estimates were for testicular cancer and melanoma of the skin (women) at 98.4% for both.
The largest difference1 in 1-year survival between men and women is for bladder cancer (11.1%): 78.0% for men and 66.9% for women. This sex difference in bladder cancer survival has been reported worldwide, and a number of reasons such as tumour biology, sex hormones and earlier diagnosis in men have been suggested to explain the difference [3, 4].
1-year survival estimates for 2010 to 2014 were up to 2.2% higher than the corresponding figure for 2009 to 2013 in men (liver cancer increasing from 34.1% to 36.3%) and up to 1.5% higher for women (lung cancer increasing from 38.9% to 40.3%, and kidney cancer increasing from 76.2% to 77.6%) (dataset table 1).
Notes for 1-year survival
- Differences are based on the exact survival estimates (see background note 9).
Figure 3 (men) and Figure 4 (women) show age-standardised 5-year net survival estimates, for adults diagnosed with 1 of the most common cancers between 2010 and 2014. Survival is below 25% for cancers of the brain, lung, oesophagus, liver, stomach, mesothelioma and pancreas in men and women. Survival estimates are above 80% for adults diagnosed with Hodgkin lymphoma, thyroid cancer and melanoma of the skin, and for breast cancer in women and testicular and prostate cancer in men.
The lowest estimate of 5-year survival was for men (5.2%) and women (6.2%) diagnosed with pancreatic cancer. The highest 5-year survival estimate among men was testis (96.8%) and for women was melanoma of the skin (92.6%). In general, 5-year survival was higher for women than men – with the notable exception of bladder cancer, which has a 9.1% difference between men (57.1%) and women (48.0%).
5-year net survival estimates for 2010 to 2014 were up to 2.3% higher1 than the corresponding figure for 2009 to 2013 in men (thyroid cancer increasing from 80.5% to 82.8%) and up to 2.1% higher for women (kidney cancer increasing from 60.8% to 62.9%) (dataset table 2).
For some cancers, 5-year survival estimates for 2010 to 2014 were slightly lower than for 2009 to 2013 (dataset table 2). For men, the largest decrease (1.4%) was for bladder cancer, from 58.6% down to 57.1%. For women, the largest decrease (1.7%) was for mesothelioma, from 11.7% to 10.0%.
Notes for 5-year survival
- Differences are calculated using unrounded survival estimates (see background note 9).
To respond to policy needs for estimates of long-term survival, 10-year survival estimates have been produced for the first time. To ensure that the 10-year estimates are timely they have been calculated using a predictive survival method. To complement and provide context for the 10-year estimates we have also provided 1- and 5-year survival estimates using the same method. Due to the predicted nature of these estimates, only cancer sites that produce robust results are included.
Figures 5 and 6 show predicted age-standardised net survival at 10-years for men and women who would be diagnosed in 2015. Survival is predicted for these patients because cancer incidence data for 2015 were not available at the time of the analysis. This is done using the hybrid approach . 10-year survival can be predicted, assuming that the conditional probabilities of surviving for patients diagnosed in 2015 are equal to those diagnosed between 2005 and 2014 (the most recent data available). The predicted estimate is conservative in a situation where survival is improving.
For men, survival is above 50% for 7 of the 8 cancers (melanoma of the skin, prostate, kidney, non-Hodgkin lymphoma, colon, colorectal and bladder) for which sufficient data are available. Consistent with 5-year survival figures, we observe the highest survival for melanoma of the skin (87.2%). Leukaemia has the lowest 10-year survival estimates at 44.8%. In women, we see a similar pattern to men for 5 of the 6 cancers for which sufficient data were available. Melanoma of the skin, breast, cervix, kidney and colorectal cancer have a survival estimate that is greater than 50%, except leukaemia, where 10-year survival is 44.7%.
The greatest difference between men and women is observed for melanoma of the skin, with 10-year survival 4.3% lower for men (87.2% versus 91.5%).
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Dataset table 5 presents age-specific predicted net survival at 1-, 5- and 10-years after diagnosis for each of the most common cancers. There are distinct patterns in survival by age group, with generally lower survival estimates among older patients, even after taking into account the fact that the elderly are also more likely to die of other causes. Two well-known exceptions to this pattern are prostate and breast cancer.
For instance, for prostate cancer (Figure 7), 5-year survival is slightly higher for men aged 50 to 69 years (ranging from 93.1% to 93.9%) than for men aged 15 to 49 years (at 92.6%). This trend remains consistent for 1- and 10-year survival. This may be partly due to more widespread (but not national) use of the prostate-specific antigen (PSA) test in older men.
A similar trend can be seen for breast cancer in 1-year, 5-year and 10-year survival estimates (Figure 8). Survival is higher for women aged 40 to 69 than for their younger peers (15 to 39 year olds). For example, 5-year survival is lower for women aged 15 to 39 years at diagnosis (85.5%) than for women aged 40 to 69 years (ranging from 90.7% to 93.0%). These differences are probably explained at least in part by breast screening for women aged 50 to 70, and by the National Health Service introducing an age extension trial in 2009 , where some younger women (aged 47 to 49 years) and some older women (aged 71 to 73 years) are invited for screening. The national breast cancer screening programme identifies cancer patients at an earlier stage than in older age groups . Screening aims to detect a tumour at an earlier stage of cancer, which helps improve survival.
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Overall, cancer survival has been improving steadily in England but it is still lower than in comparably wealthy countries. Findings from the CONCORD-2 study have shown that 5-year survival for adult patients in England diagnosed between 2005 and 2009 with leukaemia and cancers of the stomach, colon, rectum, liver, lung, breast, cervix, ovary and prostate is still lower than in Australia, Canada, Denmark, Norway and Sweden . A study  using more recent data has shown that England is not closing the international gap, with survival from cancers of the stomach, colon, rectum, lung and ovary remaining lower than, in particular, Australia, Canada, Norway and Sweden.Back to table of contents
Health policymakers use population-based cancer survival statistics to plan services aimed at cancer prevention and treatment. Cancer survival estimates feed in to national cancer plans, such as Achieving world-class cancer outcomes: A Strategy for England 2015 to 2020 . The report recommends 6 strategic priorities to help improve cancer survival in England by 2020.
Cancer survival estimates also feed into outcomes strategies that set out how the National Health Service (NHS), public health and social-care services will contribute to the progress agreed with the Secretary of State, in each of the high-level outcomes frameworks. The indicators set for the NHS Outcomes Framework 2015 to 2016  include 1- and 5-year survival from colorectal, breast and lung cancers.Back to table of contents
Table 1: Codes in the International Classification of Diseases, tenth revision (ICD-10)
|Table 1: Codes in the International Classification of Diseases, tenth revision (ICD-10)|
|Colorectum||C18 to C20, C21.8|
|Kidney||C64 to C66, C68|
|Leukaemia||C91 to C95|
|Lung||C33 and C34|
|Melanoma of skin||C43|
|Non-Hodgkin lymphoma||C82 to C85|
|Ovary||C56 to C57.7|
|Rectum||C19 to C20, C21.8|
|Uterus||C54 and C55|
|Sources: World Health Organization. International Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10) and International Classification of Diseases for Oncology, Second Edition (ICD-O). Geneva: World Health Organization.|
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Office for National Statistics (2016) Cancer Registration Statistics, England: 2014
Office for National Statistics (2015) Cancer survival in England - Adults Diagnosed: 2009 to 2013, followed up to 2014
Ristau BT, Davies BJ. Disparity in bladder cancer outcomes: What's sex got to do with it? Cancer, 120: 461–463
Lyratzopoulos G, Abel GA, McPhail S, et al. Gender inequalities in the promptness of diagnosis of bladder and renal cancer after symptomatic presentation: evidence from secondary analysis of an English primary care audit survey. BMJ Open. 2013
Public Health England (2015) Breast screening age extension trial for women who are younger than 50 or older than 70
Allemani C, Weir HK, Carreira H, Harewood R, Spika D, Wang X-S, et al. Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2). The Lancet. 2015;385:977–1010
Walters S, Benitez-Majano S, Muller P, Coleman MP, Allemani C, Butler J, et al. Is England closing the international gap in cancer survival? British Journal of Cancer. 2015;113:848-60
Independent Cancer Taskforce (2015) Achieving world-class cancer outcomes: A Strategy for England 2015-2020
Department of Health (2014) NHS Outcomes Framework 2015 to 2016
Cancer Survival Group. Life tables for England and Wales by sex, calendar period, region and deprivation. London School of Hygiene & Tropical Medicine, 2004. (updated 8 January 2016)
Brenner H, Gefeller O. Deriving more up-to-date estimates of long-term patient survival. J Clin Epidemiol 1997;50: 211–216
Pohar Perme M, Stare J, Estève J. On estimation in relative survival. Biometrics. 2012; 68:113-20.
Clerc-Urmès I, Grzebyk M, Hédelin G. Net survival estimation with stns. Stata Journal. 2014;14:87-102
Coleman MP, Babb P, Damiecki P, Grosclaude PC, Honjo S, Jones J, et al. Cancer survival trends in England and Wales 1971-1995: deprivation and NHS Region. (Studies on Medical and Population Subjects No. 61). London: The Stationery Office; 1999. p.55-106
Li R, Abela L, Moore J, Woods LM, Nur U, Rachet B, et al. Control of data quality for population-based cancer survival analysis. Cancer Epidemiol. 2014; 38:314-20
Brenner H, Rachet B. Hybrid analysis for up-to-date long-term survival rates in cancer registries with delayed recording of incident cases. Eur J Cancer 40. 2004: 2494–2501
The Quality and Methodology Information documents contain important information on:
the strengths and limitations of the data and how it compares with related data
users and uses of the data
how the output was created
the quality of the output including the accuracy of the data
More information regarding these statistics can be found in the Quality and Methodology Information (QMI) report  for cancer survival. QMI reports are overview notes which pull together important qualitative information on the various dimensions of the quality of statistics as well as providing a summary of the methods used to compile the output.Back to table of contents
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