FOI REF: FOI-2023-1429

You asked

How many cases of unplanned pregnancy has there been in women using non-enzyme-inducing antibiotics such as amoxicillin while taking oral contraceptives? Has there ever been any reported cases of a non-enzyme-inducing antibiotic such as amoxicillin having effects on estrogen concentrations caused by oral contraceptive medications?

Is the controlled medication ibuprofen an enzyme-inducing or non-enzyme-inducing drug and can it have any negative impact on oral contraceptives?

May I get a full list of non-enzyme-inducing drugs and enzyme-inducing drugs, stating both scientific and branded names?

We said

Thank you for your request.

We are responsible for the production of birth and death statistics which use registration data supplied by the General Register Office (GRO). Unfortunately, we do not hold any information on unplanned pregnancies or the effects of oral contraceptives. 

The Medicines and Healthcare Products Regulatory Agency (MHRA) may be better placed to answer your questions. You can contact them by emailing info@mhra@gov.uk.