"Figure 5: In Wales, Ischaemic heart diseases was the leading cause of death in January 2022","" "Age-standardised mortality rate for selected leading causes of death, per 100,000 people, Wales, deaths registered in January 2022","" "","" "Notes","1. Age-standardised mortality rates per 100,000 population, standardised to the 2013 European Standard Population. Monthly rates in this bulletin are adjusted to allow for comparisons with annual rates. For more information, see the [Measuring the data section](https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/monthlymortalityanalysisenglandandwales/january2022#measuring-the-data). 2. Figures for 2021 and 2022 are based on provisional mortality data and projected populations. 3. 'COVID-19' includes only deaths where COVID-19 was the underlying cause of death. 4. Figures exclude deaths of non-residents. 5. The five-year average has been provided for 2016 to 2019 and 2021 (rather than 2016 to 2020) because of the impact of the coronavirus (COVID-19) pandemic on deaths registered in 2020. The average for 2016 to 2019, and 2021, provides a comparison of the number of deaths expected per month in a usual (non-pandemic) year. Where a five-year average cannot be provided, it is denoted as "":"" in the data downloads. 6. Leading causes are ranked based on number of deaths, not age-standardised mortality rates." "Unit","Age-standardised mortality rates" "","" "Leading cause","January 2022","5-year average" "Ischaemic heart diseases","127.2","140.3" "Dementia and Alzheimer’s disease","120.7","148.6" "COVID-19","81",":" "Chronic lower respiratory diseases","60.5","85.4" "Malignant neoplasm of trachea bronchus and lung","60.7","58.1" "Cerebrovascular diseases","43.7","74.7" "Influenza and pneumonia","43.3","99.7" "Malignant neoplasm of colon sigmoid rectum and anus","32.2","30.8" "Symptoms signs and ill-defined conditions","33.0","27.4" "Malignant neoplasm of prostate","23.1","19.2"