"Figure 3: Mortality rates for deaths involving Clostridium difficile by sex, deaths registered between 2002 and 2012","" "","" "","" "Notes","1. Deaths involving Clostridium difficile are defined using a combination of any mention of International Classification of Diseases, Tenth revision (ICD 10) codes A04.7, A05.8, A41.4, A48.0, A49.8 or P36.5 anywhere on the death certificate and mention of C difficile or related conditions in the text of the death certificate. Details of the methods used can be found in the ‘Methods’ section of this bulletin. 2. The age-standardised mortality rates per million population in this bulletin were calculated using the 1976 European Standard Population. Age-standardised rates are used to allow comparison between populations which may contain different proportions of people of different ages. 3. Rates for 2002–2011 have been recalculated using revised mid-year population estimates which take account of the 2011 Census and therefore may differ from previously published figures. 4. Figures for England and Wales include deaths of non-residents. 5. Figures are based on deaths registered, rather than deaths occurring in each calendar year. In 2012 the median delay for Clostridium difficile in England and Wales was four days. Further information on registration delays for a range of causes can be found on the ONS website: www.ons.gov.uk/ons/guide-method/user-guidance/health-and-life-events/impact-of-registration-delays-on-mortality-statistics/index.html." "Unit","Age-standardised rates per million population" "","" "Year","Males","Females" "2002","15.3","15.0" "2003","18.9","19.1" "2004","23.8","23.1" "2005","37.3","38.8" "2006","66.3","64.6" "2007","85.9","80.9" "2008","62.7","56.3" "2009","39.5","37.3" "2010","25.9","25.9" "2011","20.0","19.2" "2012","15.9","14.7"