"Figure 1: Deaths involving volatile substances have remained stable over time","" "Age-standardised mortality rates for deaths related to volatile substances, by sex, England and Wales, registered from 2001 to 2020","" "","" "Notes","1. Age-standardised mortality rates per 1 million population, standardised to the 2013 European Standard Population. 2. Cause of death was defined using the International Classification of Diseases, Tenth Revision (ICD-10). 3. Figures are for deaths registered, rather than deaths occurring in each calendar year. 4. Rates are not calculated where there are fewer than three deaths, as rates based on such low numbers are susceptible to inaccurate interpretation." "Unit"," Age-standardised mortality rate per 1 million population" "","" "Year","Persons","Males","Females" "2001","0.8","1.3","0.3" "2002","1.0","1.6","0.5" "2003","0.6","0.8","0.4" "2004","0.7","1.1","0.4" "2005","0.6","1.0","0.3" "2006","0.6","0.9","0.2" "2007","0.6","1.1","0.2" "2008","0.4","0.8","" "2009","0.5","0.9","0.1" "2010","0.6","0.8","0.3" "2011","0.6","1.1","0.1" "2012","0.5","0.7","0.3" "2013","0.9","1.5","0.3" "2014","0.7","1.0","0.4" "2015","0.6","0.8","0.4" "2016","0.6","1.1","0.1" "2017","0.6","1.0","0.2" "2018","0.6","1.0","0.2" "2019","0.4","0.6","0.2" "2020","0.4","0.6","0.2"